Lirafugratinib

SI-7549

Lirafugratinib, >98% (HPLC)

CAS No. : [2549174-42-5]

Synonyms : RLY-4008

IUPAC Name : N-(4-(4-Amino-5-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl)methacrylamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Lirafugratinib selectively and irreversibly inhibits FGFR2 with nanomolar potency by covalently binding to Cys491. It effectively suppresses FGFR2‑driven signaling, including resistant variants, and produces strong tumor regression while sparing FGFR1, FGFR3, and FGFR4.

References : Subbiah V. et al.: Cancer Discov., 13(9), 2012-2031, 2023.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.