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Lisinopril impurity 3

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SL-4530

Lisinopril impurity 3, >98%

IUPAC Name : N2-((S)-1-Carboxy-3-phenylpropyl)-N6-(((S)-1-carboxy-3-phenylpropyl)-D-lysyl)-L-lysyl-L-proline

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We accept
Chemical Properites
Mol. Formula :
C37H53N5O8
Mol. Weight :
695.86
Appearance :
White to Off-white solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Lisinopril (Lisinopril EP impurity 3), which is is an angiotensin-converting enzyme (ACE) inhibitor, used in treatment of hypertension, congestive heart failure, and heart attacks, and also in preventing renal and retinal complications of diabetes.

References : Nemoto S. et al.: J. Am Coll Cardiol, 40(1), 149-154, 2002; Swaan P. W. et al.: Biochim Biophys Acta,1236(1), 31-38, 1995; Mantle D. et al.: Clin Chim Acta, 299(1-2), 1-10, 2000; Mohammadi-Karakani A. et al.: Clin Chim Acta, 367(1-2), 170-174, 2006; Duman S. et al.: Int. J. Artif Organs, 28(2), 156-163,2005; Selim Isbir C. et al.: Cell Biochem Funct, 18(2), 85-91,2000.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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