LLY-283

SI-6662

LLY-283, >98% (HPLC)

CAS No. : [2040291-27-6]

IUPAC Name : (2R,3R,4S,5R)-2-(4-Amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-5-((R)-hydroxy(phenyl)methyl)tetrahydrofuran-3,4-diol

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : LLY‑283 is an orally active, selective PRMT5 inhibitor that displays low‑nanomolar potency (IC₅₀= 22 nM; Kd = 6 nM for PRMT5:MEP50). It effectively suppresses PRMT5‑driven methylation and shows strong antitumor activity.

References : Zahid Q. Bonday. et al.: ACS. Med. Chem. Lett., 9 (7), pp 612-617, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.