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Lomitapide mesylate

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SI-3959

Lomitapide mesylate, >98% (HPLC)

CAS No. : [202914-84-9]

MDL No. : MFCD19443682

Synonyms : BMS-201038 mesylate; AEGR-733 mesylate

IUPAC Name : N-(2,2,2-Trifluoroethyl)-9-(4-(4-(4'-(trifluoromethyl)-[1,1'-biphenyl]-2-ylcarboxamido)piperidin-1-yl)butyl)-9H-fluorene-9-carboxamide mesylate

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Chemical Properites
Mol. Formula :
C39H37F6N3O2 . CH3SO2OH
Mol. Weight :
789.83
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Lomitapide mesylate is a potent inhibitor of microsomal triglyceride-transfer protein (MTP) with an IC50 of 8 nM in vitro

References : Ding X. H. et al.: Bioorg. Med. Chem. 23(9), 1895-1922, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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