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Loperamide EP impurity H

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SL-3481

Loperamide EP impurity H, >98%

CAS No. : [61299-42-1]

Synonyms : Dehydro-loperamide

IUPAC Name : 4-(4-(4-Chlorophenyl)-5,6-dihydropyridin-1(2H)-yl)-N,N-dimethyl-2,2-diphenylbutanamide

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Chemical Properites
Mol. Formula :
C29H31ClN2O
Mol. Weight :
459.02
Appearance :
Off-white solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Loperamide (Loperamide EP impurity H), which is a selective μ-opioid receptor agonist, used against diarrhea resulting from gastroenteritis or inflammatory bowel disease.

References : DeHaven-Hudkins D. L. et al.: J. Pharmacol Exp Ther., 289(1), 494-502, 1999; Quinney S. K. et al. J. Pharmacol Exp Ther., 313(3), 1011-1016, 2005; Church J. et al.: Mol. Pharmacol., 45(4), 747-757, 1994.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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