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Lopinavir metabolite M-3/M-4

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Lopinavir metabolite M-3/M-4, >98% (HPLC)

CAS No. : [357275-54-8]

MDL No. : MFCD09840843

Synonyms : 4-Hydroxy lopinavir

IUPAC Name : (2S)-N-((2S,4S,5S)-5-(2-(2,6-Dimethylphenoxy)acetamido)-4-hydroxy-1,6-diphenylhexan-2-yl)-2-(4-hydroxy-2-oxotetrahydropyrimidin-1(2H)-yl)-3-methylbutanamide

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Chemical Properites
Mol. Formula :
C37H48N4O6
Mol. Weight :
644.80
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
Acetonitrile
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a major metabolite of Lopinavir, which is an HIV protease inhibitor that displays antiviral and anticancer activities. Also, this is a COVID-19 related research chemical.

References : Sham H. L. et al.: Antimicrob Agents Chemother., 42(12), 3218-3224, 1998; Kumar G. N. et al. Drug Metab Dispos, 27(1), 86-91, 1999; Vishnuvardhan D. et al.: AIDS, 17(7), 1092-1094, 2003.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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