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CAS No. : [1454846-35-5]
MDL No. : MFCD28144520
Synonyms : PF-06463922
IUPAC Name : (R)-26-Amino-55-fluoro-11,4,7-trimethyl-6-oxo-11H-3-oxa-7-aza-2(3,5)-pyridina-1(4,3)-pyrazola-5(1,2)-benzenacyclooctaphane-15-carbonitrile
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 100MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 250MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 500MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 1G | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 5G | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 10G | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C21H19FN6O2 | Mol. Weight : 406.42 |
Appearance : Solid | Melting Point : Not available |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : Lorlatinib is a selective, orally active, brain-penetrant and ATP-competitive ROS1/ALK inhibitor. It is used for the potential treatment of non-small cell lung cancer (NSCL).
References : Johnson T. W. et al.: J. Med Chem., 57(11), 4720-44, 2014; Zou H. Y. et al.: Proc Natl Acad Sci U S A. 112(11), 3493-8, 2015.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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