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Losartan-d3 EP impurity K

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SL-5095

Losartan-d3 EP impurity K, >98%

CAS No. : [1184999-26-5]

Synonyms : EXP 3179-d3; DuP 167-d3

IUPAC Name : 2-(Butyl-d3)-4-chloro-1-[[2’-(1H-tetrazol-5-yl)[1,1’-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxaldehyde

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Chemical Properites
Mol. Formula :
C22H18D3ClN6O
Mol. Weight :
423.92
Appearance :
Off-white solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a deuterium labelled version an impurity or metabolite of Losartan (Losartan-d3 EP impurity K), which is an angiotensin II antagonist receptor blocker (ARB), used to treat high blood pressure, diabetic kidney disease, heart failure, and left ventricular enlargement.

References : Burnier M. Circulation 103(6), 904-12, 2001; Jung E. K. et al.: Korean J. Physiol Pharmacol, 14(5), 299–304, 2010; Yao E. H. et al.: Hypertens Res, 30(11), 1119-28, 2007.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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