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Losartan isomer N2-trityl impurity

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SL-5099

Losartan isomer N2-trityl impurity, >98%

CAS No. : [150098-04-7]

IUPAC Name : (2-Butyl-5-chloro-1-((2'-(2-trityl-2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-imidazol-4-yl)methanol

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Chemical Properites
Mol. Formula :
C41H37ClN6O
Mol. Weight :
665.24
Appearance :
Off-white solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Losartan, which is an angiotensin II antagonist receptor blocker (ARB), used to treat high blood pressure, diabetic kidney disease, heart failure, and left ventricular enlargement.

References : Burnier M. Circulation 103(6), 904-12, 2001; Jung E. K. et al.: Korean J. Physiol Pharmacol, 14(5), 299–304, 2010; Yao E. H. et al.: Hypertens Res, 30(11), 1119-28, 2007.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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