Losmapimod

SI-5146

Losmapimod, >98% (HPLC)

CAS No. : [585543-15-3]

MDL No. : MFCD16619322

Synonyms : GSK-AHAB; GW-856553X; SB-856553

IUPAC Name : 6-(5-(Cyclopropylcarbamoyl)-3-fluoro-2-methylphenyl)-N-neopentylnicotinamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
1G	Request A Quote		Back Order	Estimated to ship on 04 October 2026
5G	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Losmapimod is a selective, potent, and orally active p38 MAPK inhibitor with pKis of 8.1 and 7.6 for p38α and p38β, respectively. Losmapimod is under clinical trials for the potential treatment of facioscapulohumeral muscular dystrophy (FSHD).

References : Willette R. N. et al.: J. Pharmacol Exp Ther., 330(3), 964-970, 2009; Zhang X. M. et al.: Neurochem Int., 90, 1-8,2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.