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CAS No. : [2401892-75-7]
Synonyms : PF-07081532
IUPAC Name : 2-((4-((S)-2-(5-Chloropyridin-2-yl)-2-methylbenzo[d][1,3]dioxol-4-yl)piperidin-1-yl)methyl)-1-(((S)-oxetan-2-yl)methyl)-1H-benzo[d]imidazole-6-carboxylic acid
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 5MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 10MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 25MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 50MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 100MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C31H31ClN4O5 | Mol. Weight : 575.06 |
Appearance : Solid | Melting Point : Not available |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : Lotiglipron is an orally active small‑molecule GLP‑1 receptor agonist that enhances GLP‑1R‑mediated cAMP signaling to lower glucose and reduce body weight. It serves as a useful research tool compound for studying type 2 diabetes mellitus (T2DM) and metabolic regulation.
References : Buckeridge C. et al.: Hybrid 58th EASD Annual Meeting; Sept 19–23, (abstr 114), 2022; Sloop K. W. et al.: Sci. Transl. Med., 16(778), eadp5765, 2024.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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