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LP-922761

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SI-7007

LP-922761, >98% (HPLC)

CAS No. : [1454808-95-7]

IUPAC Name : tert-Butyl (2-((3-(4-carbamoylphenyl)imidazo[1,2-b]pyridazin-6-yl)amino)ethyl)(methyl)carbamate

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Chemical Properites
Mol. Formula :
C21H26N6O3
Mol. Weight :
410.48
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : LP‑922761 is a potent oral AAK1 inhibitor (IC50 = 4.8–7.6 nM) that also inhibits BIKE (24 nM) with no significant GAK or GPCR off‑target activity.

References : Kostich W. et al.: J. Pharmacol. Exp. Ther., 358(3), 371-86, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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