LP-935509

SI-6977

LP-935509, >98% (HPLC)

CAS No. : [1454555-29-3]

IUPAC Name : Isopropyl 4-(3-(2-methoxypyridin-3-yl)pyrazolo[1,5-a]pyrimidin-5-yl)piperazine-1-carboxylate

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : LP‑935509 is an orally bioavailable, ATP‑competitive AAK1 inhibitor with high potency (IC₅₀ = 3.3 nM; K_i = 0.9 nM) and confirmed brain penetration. It also inhibits BIKE with nanomolar potency and shows modest activity against GAK. LP‑935509 produces antinociceptive effects in vivo and serves as a valuable tool compound for neuropathic pain and SARS‑CoV‑2 research.

References : Kostich W. et al.: J. Pharmacol. Exp. Ther., 358(3), 371-86, 2016; Louis J. V. et al.: Neuropharmacology, 118, 167-174, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.