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LSN-3160440

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SI-7026

LSN-3160440, >98% (HPLC)

CAS No. : [2765539-59-9]

IUPAC Name : 1-((R)-1-(2,6-Dichloro-3-methoxyphenyl)ethyl)-6-(2-((R)-piperidin-2-yl)phenyl)-1H-benzo[d]imidazole

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Chemical Properites
Mol. Formula :
C27H27Cl2N3O
Mol. Weight :
480.43
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : LSN-3160440 functions as an allosteric GLP‑1R modulator that serves as a protein–protein interaction stabilizer, facilitating the binding of inactive GLP‑1(9‑36)‑NH2 to the receptor. This molecular‑glue activity supports its use in probing GLP‑1R signaling mechanisms.

References :
Hui-Jun L. et al.: Metabolites, 12(6), 549, 2022; Hongyu W. et al.: Acta. Pharm. Sin B., 12(9), 3548-3566, 2022.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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