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LSN3227716 impurity

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LSN3227716 impurity, >98%

IUPAC Name : N-(5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-yl)-5-fluoro-2-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-4-amine

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5MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
10MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
25MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
50MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
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In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C27H32F2N8
Mol. Weight :
506.61
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
Acetonitrile
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Abemaciclib, which is a selective CDK4/6 inhibitor. Abemaciclib is used for the treatment of breast cancer.

References : Ku B. M. et al.: Oncotarget., 7(12), 14803-13, 2016; Yadav V. et al.: Mol Cancer Ther., 13(10), 2253-63, 2014; Gelbert L. M. et al.: Invest New Drugs 32(5), 825-37, 2014.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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