Lumacaftor

SI-6560

Lumacaftor, >98% (HPLC)

CAS No. : [936727-05-8]

Synonyms : VRT-826809; VX-809

IUPAC Name : 3-(6-(1-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)cyclopropane-1-carboxamido)-3-methylpyridin-2-yl)benzoic acid

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
1G	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Lumacaftor acts as a CFTR‑corrector by improving the folding stability and intracellular trafficking of misprocessed CFTR protein, supporting restoration of CFTR function in cystic‑fibrosis models.

References : Van Goor F. et al.: Proc. Natl. Acad. Sci., U S A. 108(46), 18843-8, 2011;
Phuan P. W. et al.: Mol. Pharmacol., 86(1), 42-51, 2014.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.