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Lurasidone enantiomer

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Lurasidone enantiomer, >98%

CAS No. : [1448443-35-3]

Synonyms : Lurasidone (1S,2S)-exo isomer

IUPAC Name : (3aR,4S,7R,7aS)-2-(((1S,2S)-2-((4-(Benzo[d]isothiazol-3-yl)piperazin-1-yl)methyl)cyclohexyl)methyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione

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Chemical Properites
Mol. Formula :
C28H36N4O2S
Mol. Weight :
492.68
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : This is enantiomer of Lurasidone, which is an antagonist of both dopamine D2 and 5-HT7. It is also a partial agonist of 5-HT1A receptor. Lurasidone is used for the treatment of schizophrenia.

References : Ishibashi T. et al.: J. Pharmacol Exp Ther., 334(1), 171-81, 2010; Sakine Atila K. et al.: Marmara Pharm J. 21(4), 931-937, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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