Luvixasertib

SI-6627

Luvixasertib, >98% (HPLC)

CAS No. : [1610759-22-2]

Synonyms : CFI-402257

IUPAC Name : N-Cyclopropyl-4-(7-((((1s,3s)-3-hydroxy-3-methylcyclobutyl)methyl)amino)-5-(pyridin-3-yloxy)pyrazolo[1,5-a]pyrimidin-3-yl)-2-methylbenzamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : CFI‑402257 targets the mitotic kinase TTK/Mps1 with low‑nanomolar potency (IC₅₀ = 1.7 nM) and is orally bioavailable. It effectively suppresses TTK‑driven mitotic signaling and displays robust anticancer efficacy.

References : Liu Y. et al.: ACS. Med. Chem. Lett., 7(7), 671-5, 2016; Mason J. M. et al.: Proc. Natl. Acad. Sci., U S A. 114(12), 3127-3132, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.