Luxdegalutamide

SI-7260

Luxdegalutamide, >98% (HPLC)

CAS No. : [2750830-09-0]

Synonyms : ARV-766; JSB-462

IUPAC Name : 4-(4-((1-(4-(((1r,3r)-3-(4-Cyano-3-methoxyphenoxy)-2,2,4,4-tetramethylcyclobutyl)carbamoyl)phenyl)piperidin-4-yl)methyl)piperazin-1-yl)-N-((S)-2,6-dioxopiperidin-3-yl)-2-fluorobenzamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Luxdegalutamide selectively recruits AR—including resistance‑linked variants—to an E3 ligase complex, driving ubiquitination and degradation. Its oral activity and ability to eliminate mutant AR support its use in probing AR‑dependent mechanisms in castration‑resistant prostate cancer.

References : Snyder L. et al.: Drug Metabolism and Pharmacokinetics, 55, 100881, 2024; Snyder L. et al.: Cancer Research., 83(7), ND03-ND03, 2023.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.