LX-039

SI-8089

LX-039, >98% (HPLC)

CAS No. : [2135341-09-0]

IUPAC Name : (E)-3-(4-((E)-1-(3-Chloro-1H-indol-2-yl)-2-(2-chloro-4-fluorophenyl)but-1-en-1-yl)phenyl)acrylic acid

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : LX‑039 is an orally active SERD with strong potency (EC₅₀= 2.29 nM) and an indole C‑3 chlorine moiety. It demonstrates excellent pharmacokinetic behavior in mice, characterized by low clearance and high systemic exposure, and exhibits notable antitumor efficacy.

References : Lu J. et al.: Bioorg. Med. Chem. Lett., 66, 128734, 2022.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.