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LY-2090314

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SI-6355

LY-2090314, >98% (HPLC)

CAS No. : [603288-22-8]

IUPAC Name : 3-(9-Fluoro-2-(piperidine-1-carbonyl)-1,2,3,4-tetrahydro-[1,4]diazepino[6,7,1-hi]indol-7-yl)-4-(imidazo[1,2-a]pyridin-2-yl)-1H-pyrrole-2,5-dione

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Chemical Properites
Mol. Formula :
C28H25FN6O3
Mol. Weight :
512.55
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : LY-2090314 potently inhibits both GSK‑3α and GSK‑3β at low‑nanomolar concentrations, providing a robust chemical probe for studying GSK‑3‑dependent cellular and disease processes.

References : Zamek-Gliszczynski M. J. et al.: Drug Metab. Dispos., 41(4), 714-26, 2013; Atkinson J. M. et al.: PLoS One, 10(4), e0125028, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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