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LY-2828360

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SI-7284

LY-2828360, >98% (HPLC)

CAS No. : [1231220-79-3]

IUPAC Name : 8-(2-Chlorophenyl)-2-methyl-6-(4-methylpiperazin-1-yl)-9-(tetrahydro-2H-pyran-4-yl)-9H-purine

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Chemical Properites
Mol. Formula :
C22H27ClN6O
Mol. Weight :
426.95
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : LY-2828360 engages CB2 with a slow onset of action yet strong efficacy, producing G‑protein‑biased signaling marked by inhibition of cAMP production and activation of ERK1/2 pathways.

References : Lin X. et al.: Mol. Pharmacol., 93(2), 49-62, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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