LY-2874455

SI-6727

LY-2874455, >98% (HPLC)

CAS No. : [1254473-64-7]

IUPAC Name : (R,E)-2-(4-(2-(5-(1-(3,5-Dichloropyridin-4-yl)ethoxy)-1H-indazol-3-yl)vinyl)-1H-pyrazol-1-yl)ethan-1-ol

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : LY-2874455 is a low‑nanomolar inhibitor of FGFR1–4, showing strong and balanced activity across the FGFR family (IC₅₀ = 2.6–6.4 nM). It serves as a valuable tool for probing FGFR‑dependent tumor biology and resistance mechanisms.

References : Zhao G. et al.: Molecular Cancer Therapeutics., 10(11), 2200-2210, 2011.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.