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LY-3127760

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SI-7927

LY-3127760, >98% (HPLC)

CAS No. : [1529760-74-4]

IUPAC Name : 4-(6-(4-Hydroxypiperidin-1-yl)-3-methylpicolinamido)-3,5-dimethylbenzoic acid

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Chemical Properites
Mol. Formula :
C21H25N3O4
Mol. Weight :
383.45
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : LY-3127760 selectively blocks EP4 signaling with a Kiof 58 nM and a cAMP IC50 of 5.6 nM. Its potency and receptor selectivity make it valuable for studying EP4‑dependent inflammatory, immune, and tumor‑associated processes.

References : Blanco M. J. et al.: Bioorg. Med. Chem. Lett., 26, 2303–2307, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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