LY-3154885

SI-6963

LY-3154885, >98% (HPLC)

CAS No. : [2379422-72-5]

IUPAC Name : 2-(2,6-Dichlorophenyl)-1-((1S,3R)-3-(hydroxymethyl)-1-methyl-5-(1-methyl-1H-pyrazol-4-yl)-3,4-dihydroisoquinolin-2(1H)-yl)ethan-1-one

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : LY-3154885 acts as a selective, orally active D1 receptor PAM that potentiates dopamine‑dependent signaling. Its optimized pharmacokinetic properties contribute to a reduced DDI liability, making it a valuable tool for studying D1‑mediated neurocircuitry and therapeutic mechanisms.

References :
Junliang H. et al.: J. Med. Chem., 65(5), 3786-3797, 2022.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.