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LY-3202626

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SI-6158

LY-3202626, >98% (HPLC)

CAS No. : [1628690-73-2]

IUPAC Name : N-(3-((4aR,7aS)-2-Amino-6-(5-fluoropyrimidin-2-yl)-4a,5,6,7-tetrahydropyrrolo[3,4-d][1,3]thiazin-7a(4H)-yl)-4-fluorophenyl)-5-methoxypyrazine-2-carboxamide

Price And Availability
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25MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
50MGRequest A Quote
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100MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
250MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
500MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C22H20F2N8O2S
Mol. Weight :
498.51
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : LY-3202626 is a highly potent BACE1/2 inhibitor with excellent CNS penetration, showing sub‑nanomolar inhibition of BACE1 (0.615 nM) and BACE2 (0.871 nM). It is widely used to investigate amyloid‑β production and BACE‑dependent pathways in neurodegeneration.

References : McKinzie D. L. et al.: J. Med. Chem., 64(12), 8076-8100, 2021.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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