LY-3405105

SI-6913

LY-3405105, >98% (HPLC)

CAS No. : [2326428-25-3]

Synonyms : CDK7-IN-4

IUPAC Name : (E)-1-(4-(Dimethylamino)but-2-enoyl)pyrrolidin-3-yl 4-((3-isopropyl-5-methylpyrazolo[1,5-a]pyrimidin-7-yl)amino)piperidine-1-carboxylate

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : LY-3405105 potently targets CDK7 and displays broad anticancer activity, inhibiting the in‑vitro growth of diverse tumor cell lines such as colon, breast, lung, ovarian, and gastric models. Its dose‑dependent effects highlight its relevance for studying CDK7‑mediated transcriptional regulation in cancer.

References : Georgina P. Sava et al.: Cancer Metastasis Rev., 39(3), 805-823, 2020.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.