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LY-3405105

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SI-7812

LY-3405105, >98% (HPLC)

CAS No. : [2326428-25-3]

Synonyms : CDK7-IN-4

IUPAC Name : (E)-1-(5-Methylhex-2-enoyl)pyrrolidin-3-yl 4-((3-isopropyl-5-methylpyrazolo[1,5-a]pyrimidin-7-yl)amino)piperidine-1-carboxylate

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Chemical Properites
Mol. Formula :
C27H40N6O3
Mol. Weight :
496.66
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This potently targets CDK7 and displays broad anticancer activity, suppressing the in‑vitro growth of diverse tumor cell lines such as colon, breast, lung, ovarian, and gastric models in a dose‑dependent manner. Its activity profile underscores its relevance for studying CDK7‑mediated transcriptional regulation in cancer.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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