LY-3522348

SI-7384

LY-3522348, >98% (HPLC)

CAS No. : [2568608-48-8]

Synonyms : KHK-IN-3

IUPAC Name : (S)-2-(4-(2-(2-Methylazetidin-1-yl)-6-(trifluoromethyl)pyrimidin-4-yl)-1H-pyrazol-1-yl)-1-(piperazin-1-yl)ethan-1-one

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : LY-3522348 inhibits ketohexokinase, the key enzyme that phosphorylates fructose to fructose‑1‑phosphate (F1P) using ATP. The unregulated nature of fructose metabolism results in buildup of intermediates that stimulate lipogenesis, gluconeogenesis, and mitochondrial oxidative pathways. LY-3522348 is applied in research on kidney disease, NASH, diabetes, and heart failure.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.