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M-1069

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SI-7588

M-1069, >98% (HPLC)

CAS No. : [3027658-65-4]

IUPAC Name : (S)-N-(7-(3,6-Dihydro-2H-pyran-4-yl)-4-methoxythiazolo[4,5-c]pyridin-2-yl)-7-oxa-2-azaspiro[4.5]decane-2-carboxamide fumarate

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Chemical Properites
Mol. Formula :
C21H26N4O4S • C4H4O4
Mol. Weight :
546.6
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : M-1069 selectively inhibits A2A and A2B receptors with >100‑fold selectivity over A1/A3, effectively reversing adenosine‑mediated immune suppression. It displays antitumor efficacy, supporting its use in immuno‑oncology research.

References : Zaynagetdinov et R. al.: Cancer Res., 82 (12), 3499, 2022; Siu L. L. et al.: Cancer Res., 82(12), CT240, 2022.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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