M-2698

SI-6811

M-2698, >98% (HPLC)

CAS No. : [1379545-95-5]

Synonyms : MSC-2363318A

IUPAC Name : (S)-4-((2-(Azetidin-1-yl)-1-(4-chloro-3-(trifluoromethyl)phenyl)ethyl)amino)quinazoline-8-carboxamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : M-2698 selectively inhibits p70S6K and Akt isoforms (Akt1/Akt3) with IC₅₀ values of 1 nM and functions as an ATP‑competitive kinase inhibitor. It is orally active, brain‑penetrant, and displays robust anticancer activity in models driven by dysregulated PI3K/Akt signaling.

References : Machl A. et al.: Am. J. Cancer Res., 6(4), 806-18, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.