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M-808

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SI-6138

M-808, >98% (HPLC)

CAS No. : [2377335-74-3]

IUPAC Name : Methyl ((1S,2R)-2-((S)-2-(azetidin-1-yl)-1-(3-fluorophenyl)-1-(1-((1-(4-((1-((E)-4-(piperidin-1-yl)but-2-enoyl)azetidin-3-yl)sulfonyl)phenyl)azetidin-3-yl)methyl)piperidin-4-yl)ethyl)cyclopentyl)carbamate

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Chemical Properites
Mol. Formula :
C45H63FN6O5S
Mol. Weight :
819.09
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : M‑808 is a covalent Menin–MLL inhibitor with a binding IC50 of 2.6 nM, demonstrating strong target engagement and high potency against the Menin–MLL interaction.

References : Xu S. et al.: J. Med. Chem., 63(9), 4997-5010, 2020.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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