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Macitentan-d4

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Macitentan-d4, >98% (HPLC)

Isotopic Purity : 98 atom % D

CAS No. : [1258428-05-5]

Synonyms : ACT-064992-d4

IUPAC Name : N-[5-(4-Bromophenyl)-6-[2-[(5-bromo-2-pyrimidinyl)oxy](ethoxy-d4)]-4-pyrimidinyl]-N’-propyl-sulfamide

Price And Availability
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5MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
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In Stock  Estimated to ship on 20 September 2026
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In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C19H16D4Br2N6O4S
Mol. Weight :
592.30
Appearance :
White solid
Melting Point :
Not available
Solubility :
Methanol
For Laboratory research use only, not for drug, household or other uses.

Applications : Macitentan-d4 is a deuterium labelled version of Macitentan, which is an orally active, non-peptide endothelin receptor antagonist for the treatment of idiopathic pulmonary fibrosis and pulmonary arterial hypertension.

References : Iglarz M. et al. J. Pharmacol Exp Ther., 327(3), 736-745, 2008; Sen S. et al.: Life Sci., 91(13-14), 658-668, 2012; Kim S. J. et al.: Neoplasia., 13(2), 167-179, 2011.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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