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SI-7866

Magnolin, >98% (HPLC)

CAS No. : [31008-18-1]

Synonyms : TOV-112D

IUPAC Name : (1S,3aR,4S,6aR)-1-(3,4-Dimethoxyphenyl)-4-(3,4,5-trimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan

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Chemical Properites
Mol. Formula :
C23H28O7
Mol. Weight :
416.47
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Magnolin, a major component of Magnolia liliiflora, selectively inhibits ERK1 and ERK2 (IC50 = 87 nM and 16.5 nM) and blocks downstream Ras/ERKs/RSK2 signaling. Its potent ERK inhibition supports its use in MAPK‑pathway research.

References : Lee C. J. et al.: BMC Cancer, 15, 576, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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