MAK-683-CH2CH2COOH

SI-6877

MAK-683-CH2CH2COOH, >98% (HPLC)

CAS No. : [2639882-68-9]

IUPAC Name : 3-(5-(5-(((5-Fluoro-2,3-dihydrobenzofuran-4-yl)methyl)amino)-[1,2,4]triazolo[4,3-c]pyrimidin-8-yl)-6-methylpyridin-2-yl)propanoic acid

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : MAK-683‑CH₂CH₂COOH retains high affinity for EED and functions as the target‑binding component in EED‑directed PROTACs. When linked to a VHL‑recruiting ligand, which promote EED ubiquitination and degradation.

References : Hsu J. H. et al.: Cell Chem. Biol., 27(1), 41-46.e17, 2020.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.