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Maribavir

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SL-10966

Maribavir, >98%

CAS No. : [176161-24-3]

Synonyms : BW1263W94; GW257406X; 1263W94

IUPAC Name : (2R,3R,4S,5R)-2-(5,6-Dichloro-2-(isopropylamino)-1H-benzo[d]imidazol-1-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol

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Chemical Properites
Mol. Formula :
C15H19Cl2N3O4
Mol. Weight :
376.23
Appearance :
Solid
Melting Point :
Not available
Solubility :
DMSO
For Laboratory research use only, not for drug, household or other uses.

Applications : Maribavir is a potent inhibitor of histone phosphorylation mediated by wild-type pUL97 in vitro, exhibiting an IC50 of 3 nM. Furthermore, Maribavir demonstrates substantial antiviral efficacy against human cytomegalovirus (HCMV) and Epstein-Barr virus (EBV).

References : Shannon-Lowe C. D. et al.: Herpesviridae, 1(1), 4, 2010; Biron K. K. et al.: Antimicrob Agents Chemother., 46(8), 2365-72, 2002.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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