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CAS No. : [1048007-93-7]
Synonyms : AB-1010 mesylate
IUPAC Name : N-(4-Methyl-3-((4-(pyridin-3-yl)thiazol-2-yl)amino)phenyl)-4-((4-methylpiperazin-1-yl)methyl)benzamide methanesulfonate
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 25MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 50MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 100MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 250MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 500MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C28H30N6OS • CH3SO2OH | Mol. Weight : 594.75 |
Appearance : Solid | Melting Point : Not available |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : Masitinib mesylate selectively inhibits c‑Kit with sub‑micromolar potency and also suppresses PDGFRα/β, Lyn, and Lck, with limited activity on FGFR3 and FAK. It induces anti‑proliferative and pro‑apoptotic responses and is characterized by low toxicity, making it a valuable tool for investigating c‑Kit‑mediated pathways.
References : Dubreuil P. et al.: PLoS One, 4(9), e7258, 2009; Lawrence J. et al.: Vet Comp. Oncol., 2011; Hahn K. A. et al.: J. Vet. Intern. Med., 22(6), 1301-1309, 2008; Marech I. et al.: Crit. Rev. Oncol. Hematol., 91(1), 98-111, 2014.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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