MC-180295

SI-7817

MC-180295, >98% (HPLC)

CAS No. : [2237942-08-2]

Synonyms : (rel)-MC-180295

IUPAC Name : (4-Amino-2-(((2S)-bicyclo[2.2.1]heptan-2-yl)amino)thiazol-5-yl)(2-nitrophenyl)methanone

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : MC-180295 is a highly potent CDK9–Cyclin T1 inhibitor (IC₅₀ = 5 nM) with strong selectivity over other CDKs (≥22‑fold). It also inhibits GSK‑3α/β and shows pronounced anti‑tumor effects, making it a valuable tool for probing CDK9‑dependent transcriptional pathways and oncogenic signaling.

References : Zhang H. et al.: Cell, 175(5), 1244-1258.e26, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.