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MDK-83190

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SL-047

MDK-83190, 98%

CAS No. : [79183-19-0]

MDL No. : MFCD00141556

Synonyms : 1-[(3,4-Dichlorophenyl)methyl]-1H-indole-2,3-dione

IUPAC Name : 1-(3,4-Dichlorobenzyl)-1H-indole-2,3-dione

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
10MG50.00
Back Order  Estimated to ship on 04 October 2026
25MG105.00
Back Order  Estimated to ship on 04 October 2026
50MG135.00
Back Order  Estimated to ship on 04 October 2026
100MG255.00
Back Order  Estimated to ship on 04 October 2026
250MG495.00
Back Order  Estimated to ship on 04 October 2026
500MG895.00
Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C15H9Cl2NO2
Mol. Weight :
306.14
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Apoptosis activator; promotes the cytochrome c-dependent oligomerization of Apaf-1 into the mature apoptosome. Increases procaspase-9 processing and subsequent caspase-3 activation. Induces apoptosis in tumor cells (IC50 = 4 - 9 μM for leukemia cells) with weak or no effect on normal cell lines or those defective/deficient in Apaf-1, caspase-9 or caspase-3 activity (IC50 > 40 μM).

References : Nguyen. J.T. et. al.: Proc. Natl. Acad. Sci. USA, 100, 7533, 2003.

Storage : Store at RT

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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