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MDM2-p53 inhibitor

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SI-6488

MDM2-p53 inhibitor, >98% (HPLC)

CAS No. : [2093204-79-4]

IUPAC Name : (R)-1-(((1-(4-Chlorophenyl)-2-((5-chloropyridin-2-yl)methyl)-7-fluoro-5-(2-hydroxypropan-2-yl)-3-oxoisoindolin-1-yl)oxy)methyl)cyclopropane-1-carboxamide

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Chemical Properites
Mol. Formula :
C28H26Cl2FN3O4
Mol. Weight :
558.43
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This scaffold supports mechanistic oncology research, particularly in programs targeting isoindolinone‑based protein–protein interaction modulators and next‑generation small‑molecule inhibitors.

References : Chessari G. et al.: J. Med. Chem., 64(7), 4071−4088, 2021.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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