Mebendazole amine

SL-10981

Mebendazole amine, >98%

CAS No. : [52329-60-9]

IUPAC Name : (2-Amino-1H-benzo[d]imidazol-6-yl)(phenyl)methanone

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25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
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Applications : This is an advanced key intermediate in the synthesis of Mebendazole and related analogs. Mebendazole is a highly effective broad-spectrum antihelmintic agent indicated for the treatment of nematode infestations. Additionally, Mebendazole demonstrates inhibitory activity against glioblastoma multiforme (GBM), suppresses the Hedgehog signaling pathway, and impedes tubulin polymerization. The compound is orally bioavailable and possesses the capability to penetrate the central nervous system.

References : Bai R. Y. et al.: Neuro Oncol., 13(9), 974-82, 2011; Larsen A. R. et al.: Mol Cancer Ther., 14(1), 3-13, 2015; Erdincler P. et al.: Br. J .Neurosurg., 11(2), 116-20, 1997.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.