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Mebendazole-d3

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SL-10978

Mebendazole-d3, >98%

CAS No. : [1173021-87-8]

IUPAC Name : Methyl-d3 (6-benzoyl-1H-benzo[d]imidazol-2-yl)carbamate

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Chemical Properites
Mol. Formula :
C16H10D3N3O3
Mol. Weight :
298.32
Appearance :
Solid
Melting Point :
Not available
Solubility :
DMSO
For Laboratory research use only, not for drug, household or other uses.

Applications : Mebendazole-d3 is a deuterium labelled version of Mebendazole. This can be used as an analytical labelled reference standard. Mebendazole is a highly effective broad-spectrum antihelmintic agent indicated for the treatment of nematode infestations. Additionally, Mebendazole demonstrates inhibitory activity against glioblastoma multiforme (GBM), suppresses the Hedgehog signaling pathway, and impedes tubulin polymerization. The compound is orally bioavailable and possesses the capability to penetrate the central nervous system.

References : Bai R. Y. et al.: Neuro Oncol., 13(9), 974-82, 2011; Larsen A. R. et al.: Mol Cancer Ther., 14(1), 3-13, 2015; Erdincler P. et al.: Br. J .Neurosurg., 11(2), 116-20, 1997.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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