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Medroxyprogesterone EP impurity C

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Medroxyprogesterone EP impurity C, >98%

Synonyms : D-Homo analog medroxy progesterone (imp C Ph .Eur); Medroxyprogesterone acetate EP impurity C

IUPAC Name : (1S,4aS,4bR,6S,10aR,10bS,12aS)-1,6,10a,12a-Tetramethyl-2,8-dioxo-1,2,3,4,4a,4b,5,6,8,9,10,10a,10b,11,12,12a-hexadecahydrochrysen-1-yl acetate

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5MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C24H34O4
Mol. Weight :
386.53
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Medroxyprogesterone, which is a synthetic form of human progesterone that acts as an agonist at progesterone receptors and can be taken orally. It promotes cell proliferation via the PI3K/Akt signaling pathway and has been shown to inhibit atherosclerosis in mice. However, its progesterone agonist activity is less potent compared to medroxyprogesterone acetate.

References : Saitoh M. et al.: Endocrinology, 146(11), 4917-25, 2005; Ito F. et al.: J. Clin Endocrinol Metab., 99(6), 2188-97, 2014; Freudenberger T. et al.: Br. J. Pharmacol., 158(8), 1951-60, 2009; Yusop S. N. W. et al.: Steroids, 164:108735, 2020.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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