Medroxyprogesterone (impurity B)

SL-10992

Medroxyprogesterone (impurity B), >98%

CAS No. : [520-85-4]

Synonyms : 17α-Hydroxy-6α-methyl progesterone; 17-Hydroxy-6α-methylpregn-4-ene-3,20-dione; Medroxy progesterone acetate USP related compound B; Medroxyprogesterone EP impurity B; 6α-Methyl-4-pregnen-17α-ol-3,20-dione; 6α-Methyl-17-hydroxyprogesterone; 6α-Methyl-17R-hydroxyprogesterone; 6α-Methyl-17α-hydroxypregn-4-ene-3,20-dione; 6α-Methyl-17α-hydroxyprogesterone; NSC 27408

IUPAC Name : (6S,8R,9S,10R,13S,14S,17R)-17-Acetyl-17-hydroxy-6,10,13-trimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one

Price And Availability
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1G	Request A Quote		In Stock	Estimated to ship on 20 September 2026
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Applications : This is an impurity of Medroxyprogesterone, which is a synthetic form of human progesterone that acts as an agonist at progesterone receptors and can be taken orally. It promotes cell proliferation via the PI3K/Akt signaling pathway and has been shown to inhibit atherosclerosis in mice. However, its progesterone agonist activity is less potent compared to medroxyprogesterone acetate.

References : Saitoh M. et al.: Endocrinology, 146(11), 4917-25, 2005; Ito F. et al.: J. Clin Endocrinol Metab., 99(6), 2188-97, 2014; Freudenberger T. et al.: Br. J. Pharmacol., 158(8), 1951-60, 2009; Yusop S. N. W. et al.: Steroids, 164:108735, 2020.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.