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Met(O)-27-Glucagon

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Met(O)-27-Glucagon, >95%

CAS No. : [75217-63-9]

IUPAC Name : H-His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met(O)-Asn-Thr-OH

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5MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C153H225N43O50S
Mol. Weight :
3498.79
Appearance :
White lyophilized powder
Melting Point :
Not available
Solubility :
Freely soluble 70% Acetonitrile in H2O
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Glucagon (1-29), which is derived from bovine, human, and porcine sources. It is a peptide hormone synthesized by pancreatic α-cells. This hormone stimulates gluconeogenesis and activates HNF4α, leading to an increase in HNF4α phosphorylation.

References : Song W. J. et al.: Cell Metab., 19(4), 667-81, 2014; Hirota K. et al.: J. Biol Chem., 278(15), 13056-60, 2003; Song K. H. et al.: Hepatology, 43(1), 117-25, 2006; Capozzi M. E. et al.: JCI Insight., 5, pii: 129954, 2019 Jul 23.

Storage : Keep container tightly closed under nitrogen or argon and store at -20oC for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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