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Metformin-d6

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SL-4418

Metformin-d6, >98% (HPLC)

Isotopic Purity : 99 atom % D

CAS No. : [1185512-92-8]

Synonyms : 1,1-Dimethylbiguanide-d6

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Chemical Properites
Mol. Formula :
C4H5D6N5
Mol. Weight :
135.2
Appearance :
White to Off-white solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Metformin-d6 is a deuterium labelled version of Metformin, which is decreases hyperglycemia in hepatocytes primarily by suppressing glucose production by the liver (hepatic gluconeogenesis).

References : Zhou G. et al.: J. Clin Invest, 108(8), 1167-1174, 2001; Shaw R. J. et al.: Science, 310(5754), 1642-1646, 2005; Fryer L. G. et al.: J. Biol Chem, 277(28), 25226-25232, 2002; Schmidt L. J. et al.: Prostate, 67(10), 1111-1120, 2007.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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