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Methuosis inducer

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SI-7978

Methuosis inducer, >98% (HPLC)

IUPAC Name : (E)-1-(4-Chlorophenyl)-3-(4-((4-morpholino-6-styryl-1,3,5-triazin-2-yl)amino)phenyl)urea

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Chemical Properites
Mol. Formula :
C28H26ClN7O2
Mol. Weight :
528.01
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This compound shows micromolar antiproliferative activity and induces methuosis in U87 glioblastoma cells, marked by pronounced intracellular vacuolization, confirming strong disruption of endolysosomal trafficking consistent with methuosis‑driven cell death.

References : Zhang L. et al.: Eur. J. Med. Chem., 214, 113188, 2021.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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