Methyl 2-((4S,5S)-4-methyl-1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-3-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-5-yl)acetate

SI-815

Methyl 2-((4S,5S)-4-methyl-1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-3-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-5-yl)acetate, 97%

CAS No. : [1610561-25-5]

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Applications : This is an advanced key intermediate in the preparation of BMS-986118 and related analogs, which is a potent and selective GPR40 agonist.

References : Shi J. et al.: J. Med. Chem., 61(3), 681-694, 2018

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.