Methyl (E)-3-(2-(dimethylamino)vinyl)-2-nitrobenzoate

SL-11165

Methyl (E)-3-(2-(dimethylamino)vinyl)-2-nitrobenzoate, >98%

CAS No. : [93247-79-1]

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
50MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
100MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
250MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
500MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026

Applications : This is an advanced key intermediate in the synthesis of Niraparib and related analogs. Niraparib is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor. Niraparib inhibits the repair of DNA damage, induces apoptosis, and demonstrates anti-tumor activity.

References : Jones P. et al.: J. Med. Chem., 52(22), 7170-85, 2009; Bridges K. A. et al.: Oncotarget., 5(13), 5076-86, 2014; Wang L. et al.: Invest New Drugs, 30(6), 2113-20, 2012; Mirza M. R. et al.: N. Engl. J. Med., 375(22), 2154-2164, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.