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Metopimazine acid-d6

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Metopimazine acid-d6, >93% (HPLC)

Isotopic Purity : 98 atom % D

CAS No. : [1215326-10-5]

MDL No. : MFCD15071286

Related CAS No. : [18182-00-8] of the unlabelled compound

Synonyms : 1-[3-[2-(Methylsulfonyl)phenothiazin-10-yl]propyl-d6]isonipecotic acid

IUPAC Name : 1-[3-[2-(Methylsulfonyl)-10H-phenothiazin-10-yl]propyl-d6]-4-piperidinecarboxylic acid

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Chemical Properites
Mol. Formula :
C22H20D6N2O4S2
Mol. Weight :
452.62
Appearance :
Yellow solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a deuterium labelled version metabolite of Metopimazin, which is used to prevent emesis during chemotherapies, and an antiemetic.

References : Catz P. et al.: Int. J. Pharm., 58, 93, 1990; Sato K. et al.: J. Pharm. Sci., 80, 104, 1991; Herrstedt J. et al.: Cancer Chemother. Pharmacol., 33, 53, 1996; Sigsgaard T. et al.: J. Clin. Onc., 19, 2091, 2001.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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